Trypanosomes are a major scourge of tropical Africa. Though not in the focus of public interest of the Western world, Trypanosoma brucei and related species keep on terrorizing some 36 countries South of the Sahara. Transmitted by the infamous tsetse fly, trypanosomes cause fatal diseases such as the human sleeping sickness or nagana in livestock. In addition to human disease, infection of domestic cattle by T. brucei has an enormous, but poorly quantified, negative impact on human welfare as it is difficult to rear cattle in endemic areas, where use of bovines as draught animals is frequently the only agricultural strategy available. Most critically, health agencies have essentially lost control of the disease in the last half-century due to social and geopolitical problems; consequential poor public health implementation has resulted in widespread emergence of drug resistance. Furthermore, the few available drugs are highly toxic and, thus, there is desperate need for novel medication. Hence, basic research on trypanosomes has always to keep in mind that the preferred model cell is in fact a killer. Therefore, we have initiated a long-term collaborations with scientists in Africa, especially Kenya and Uganda. We have set up a cell and molecular biology laboratory at ICIPE in Nairobi that is as well equipped as our own labs here in Würzburg (thank you, DFG!). Currently, two graduate students are working on a joint project that involves frequent exchange visits. We aim at capacity building in Africa that involves high-tech transfer. Note that the University of Würzburg has many activities related to Africa, e.g. the Afrikazentrum and fUNIKIN.