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For more than a century Cell and Developmental Biology has been one major research focus at the Zoological Institute of the Julius-Maximilians-University in Würzburg. Here, Theodor Boveri founded the chromosome theory of inheritance and Hans Spemann did his habilitation. Today, our recently refurbished department continues to provide an inspiring scientific environment for several committed research groups. We work on basic aspects of membrane biology as well as on cell motility, meiosis, epigenetics or control of gene expression. Our approach is always quantitative and interdisciplinary using state-of-the art technology. We promote the deadly African trypanosomes as powerful cell biological model system, but also work with mammalian and yeast cells, C. elegans, the claw frog Xenopus and the enigmatic hydra. Besides our passion for science we are dedicated teachers. Each year hundreds of students attend our newly designed practical courses, seminars and lectures.


November 17,

ZEB Seminar

Prof. Dr. Doris Heinrich
Institute of Physics, Uni Leiden
"Cell dynamics- from intracellular transport to artificial tissue"
20.11.2014, 9.15 Uhr, Biozentrum, Hörsaal A103

November 17,

Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes.

Gülcin Dindar, Andreas M. Anger, Christine Mehlhorn, Sandra B. Hake & Christian J. Janzen
Nature communication 5, Article number: 5313 doi:10.1038/ncomms6313

DOT1 enzymes are conserved methyltransferases that catalyse the methylation of lysine 79 on histone ​H3. Most eukaryotes contain one DOT1 enzyme, whereas African trypanosomes have two homologues, ​DOT1A and ​DOT1B, with different enzymatic activities. We employed a trypanosomal nucleosome reconstitution system and structure-guided homology modelling to identify critical residues within and outside the catalytic centre that modulate product specificity of these enzymes. … MORE

November 12,

Boveri’s microscopic slides back in Würzburg.

Famous cell biologist Joe Gall donates original slides to complete the unique selection of Boveri’s histological specimen in Würzburg. … MORE

November 11,

CDK2 and the dynamics of telomeres and nuclear envelope proteins in meiotic cells

Viera, A., M. Alsheimer, R. Gómez, I. Berenguer, S. Ortega, C.E. Saymonds, D. Santamaría, R. Benavente & J.A. Suja: CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase. J. Cell Sci. doi:10.1242/jcs.154922 … MORE

November 06,


Dr. Falk Butter, Institute of Molecular Biology, Mainz:
‘Quantitative Proteomics for Biology'
09:15 A102

October 14,

Vortrag vor 500 Schülern:

Ebola & Co.: Wenn vernachlässigte Tropenkrankheiten Schlagzeilen machen.


October 06,

The Faculty of Biology announces the ‘Center for Computational and Theoretical Biology’.

The CCTB is an independent scientific unit that will be located in newly renovated rooms at the Würzburg Campus Hubland Nord. Four junior professors covering very different aspects of computational biology will form the core of the CCTB.

October 01,

Optical trapping reveals propulsion forces, power generation and motility efficiency of the unicellular parasite Trypanosoma brucei brucei

Eric Stellamanns, Sravanti Uppaluri, Axel Hochstetter, Niko Heddergott, Markus Engstler & Thomas Pfohl
SCIENTIFIC REPORTS | 4 : 6515 | DOI: 10.1038/srep06515 1

September 04,

Founding member of Neglected Tropical Diseases Network

Markus Engstler is a founding member of DNTDs, the German network to combat neglected tropical diseases. The alliance of scientific community, civil society and private industry was inaugurated on August 27th in Berlin and is part of a global initiative

August 28,

Historical roots of centrosome research: discovery of Boveri's microscope slides in Würzburg

Ulrich Scheer
Phil. Trans. R. Soc. B 2014 369, 20130469, published 21 July 2014

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